 |
Research Article
Epidemiological surveillance and burden of serological infectious markers among adult population of New Juaben Municipality: A 6-year laboratory review from the Eastern Regional Hospital, Ghana
1 Faculty of Health and Allied Sciences, Koforidua Technical University, Koforidua, Eastern Region, Ghana
2 Department of Medical Laboratory Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana
3 Department of Medical Laboratory, Eastern Regional Hospital, Koforidua, Eastern Region, Ghana
Address correspondence to:
Francis Abeku Ussher
Koforidua Technical University, Koforidua,
Ghana
Message to Corresponding Author
Article ID: 100074Z02FU2022
Access full text article on other devices
Access PDF of article on other devices
How to cite this article
Ussher FA, Taufik O, Osei-Yeboah J, Lokpo SY, Danquah GD, Kwakye GK, Der J. Epidemiological surveillance and burden of serological infectious markers among adult population of New Juaben Municipality: A 6-year laboratory review from the Eastern Regional Hospital, Ghana. Int J Blood Transfus Immunohematol 2022;12(2):1–11.ABSTRACT
Aims: The study aimed at determining the epidemiological feature and burden of infectious markers among asymptomatic adult population in Koforidua.
Methods: This is a hospital-based retrospective study conducted at the Eastern Regional Hospital and comprised of a review of secondary data of prospective blood donors who visited the facility blood bank from January 2015 to December 2020. Archived data of 22,648 prospective blood donors comprising gender, age, and residential locations as well as results of infectious markers [syphilis, hepatitis C virus (HCV), hepatitis B virus (HBV), and human immunodeficiency virus (HIV)] were retrieved from the blood bank. Prospective blood donors were screened for infectious markers using rapid diagnostic test (RDT) kits. Hepatitis B, hepatitis C, and syphilis were screened using Abon, Micropoint, Just check, Green life, and Accurate rapid diagnostic test kits whereas HIV was screened using First response kits.
Results: The overall cumulative crude prevalence rate of blood-borne pathogens was 69.76 per 10,000, 27.45 per 10,000, 115.15 per 10,000, and 33.87 per 10,000 population for HBV, HCV, syphilis, and HIV, respectively. A prominent year-on-year decreasing trend of hepatitis B viral infection and HIV was observed in the general population. On the other hand, syphilis infection recorded an increasing trend of infection while HCV infection demonstrated a dual trend with a decrease from 2016 to 2018 and an increase till the end of 2020.
Conclusion: The overall burden of transfusion transmissible infections (TTIs) was high among the populace with a prominent male gender preponderance. The rates of the infections were highly marked among the youth population within the ages of 20 to 29 years.
Keywords: Blood donors, Crude prevalence, Transfusion transmissible infection
SUPPORTING INFORMATION
Acknowledgments
We wish to acknowledge staff of the Eastern Regional Hospital Blood Bank and the Laboratory for their invaluable contribution toward this study.
Author ContributionsFrancis Abeku Ussher - Conception of the work, Design of the work, Acquisition of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Osmanu Taufik - Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
James Osei-Yeboah - Conception of the work, Design of the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Sylvester Yao Lokpo - Conception of the work, Design of the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
George Damptey Danquah - Acquisition of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
George Kwasi Kwakye - Acquisition of data, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Joyce Der - Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2022 Francis Abeku Ussher et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
