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Technical Report
Accurate temperature representation of storage conditions of human tissue and blood products: A cold chain analysis
1 American Pharma Technologies, Pharma Watch, Vice President of Science and Engineering, 222 North 13th Street Boise, ID 83702, USA
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Michael R Rusnack
American Pharma Technologies, Pharma Watch, Vice President of Science and Engineering, 222 North 13th Street Boise, ID 83702,
USA
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Article ID: 100060Z02MR2021
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Rusnack MR. Accurate temperature representation of storage conditions of human tissue and blood products: A cold chain analysis. Int J Blood Transfus Immunohematol 2021;11:100060Z02MR2021.ABSTRACT
There is nothing of higher value than human life. A close second is a human tissue that is utilized to help prolong that human life. Proper storage and management of the environment in which these materials are being stored are critical. A common practice in monitoring cold chain conditions for these temperature-sensitive materials is to employ a physical, thermal buffer into which the temperature probe is inserted. This buffer maybe a bottle of glycol or other liquid, a container of glass beads, an aluminum block, or nearly any other media the user feels is appropriate. The purpose of the buffer is to simulate the stored product’s experience rather than the air temperature. This will not be accomplished if the physical buffer is not matched to the stored product’s thermal properties and its container. Cold chain managers are faced with a complex problem if they attempt to take this issue into account. Furthermore, a match is impossible with a single physical buffer when the cold storage unit contains different products and various container sizes. This paper addresses the results of this mismatch from multiple factors and brings to the forefront the real-world problems that may result. Additionally, this paper will discuss a demonstrated solution that will accurately represent the stored materials, no matter the packaging size, material, or contents.
Keywords: Blood storage, Remote temperature monitoring, Temperature buffer, Transportation
SUPPORTING INFORMATION
Author Contributions
Michael R Rusnack - Conception of the work, Design of the work, Analysis of data, Drafting the work, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthor declares no conflict of interest.
Copyright© 2021 Michael R Rusnack et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
