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Case Report
Thrombocytapheresis: An important therapeutic tool in the management of thrombocytosis in cerebral venous thrombosis
1 Senior Consultant and Head, Department of Transfusion Medicine and Immunohematology, Sri Balaji Action Medical Institute, A-4, Paschim Vihar, New Delhi, India
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Sadhana Mangwana
G-17, Pocket-2, Naraina Vihar, New Delhi 110028,
India
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Article ID: 100054Z02SM2020
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Mangwana S. Thrombocytapheresis: An important therapeutic tool in the management of thrombocytosis in cerebral venous thrombosis. Int J Blood Transfus Immunohematol 2020;10:100054Z02SM2020.ABSTRACT
Introduction: Therapeutic thrombocytapheresis is an effective and useful measure of platelet reduction in patients with severe thrombocytosis from various primary or secondary causes of thrombocytosis to relieve patient of debilitating complications. American Society of Apheresis (ASFA) has recommended platelet reduction by thrombocytapheresis procedures for symptomatic relief in essential thrombocythemia and polycythemia vera indications under category 2C, but other causes are not included in this category by ASFA.
Case Report: Here, a case of cerebral venous thrombosis is presented which developed severe thrombocytosis in the post-operative period as secondary (reactive) cause to acute hemorrhage and benefitted after successful therapeutic thrombocytapheresis procedures without any debilitating or residual complications of neurosurgery.
Conclusion: This case highlights the importance of therapeutic platelet reduction by a very simple and easy plateletapheresis procedure which is routinely done in many blood establishments globally for other indications.
Keywords: Plateletapheresis, Platelet reduction, Thrombocytapheresis, Thrombocytosis
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Author Contributions
Sadhana Mangwana - Conception of the work, Design of the work, Acquisition of data, Analysis of data, Drafting the work, Revising the work critically for important intellectual content, Final approval of the version to be published, Agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthor declares no conflict of interest.
Copyright© 2020 Sadhana Mangwana. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
