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Original Article
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| Evaluation of nucleic acid testing for blood donors: One year study | ||||||
| Hussain Al-Turaifi | ||||||
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Department of Laboratory and Blood Bank, King Fahad Hospital, Hufof, Kingdom of Saudia Arabia.
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| How to cite this article |
| Al-Turaifi H. Evaluation of nucleic acid testing for blood donors: One year study. Int J Blood Transfus Immunohematol 2015;5:19–25. |
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Abstract
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Aims:
Blood transfusion is an essential management to save patients life in health care system. Blood is a potential source of transmitted diseases which make the safety of blood products important issue in laboratory medicine. Investigations of transfusion-transmitted infections (TTI), especially hepatitis viruses and acquired immunodeficiency virus, are essential in all blood bank policies. Several methods were applied to screen blood products for hepatitis B and hepatitis C viruses and acquired immunodeficiency virus.
Methods: Blood donor's samples for one year were collected and examined for hepatitis viruses and acquired immunodeficiency virus by using serological and nucleic acid testing (NAT). Results: Comparative study showed that NAT is more specific than serologic screening testing for both hepatitis C virus and acquired immunodeficiency virus. However, NAT and serological tests are required to increase the safety of blood components from hepatitis B virus transmission. Conclusion: This study is an attempt to evaluate the effectiveness of introducing NAT for examination of blood components. National-wide study is required to evaluate the policy of blood screening program. | |
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Keywords:
Blood donor tests, Hepatitis virus, Nucleic acid testing (NAT), Transfusion-transmitted infections
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Author Contributions:
Hussain Al-Turaifi – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2015 Hussain Al-Turaifi et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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