International Journal of Blood Transfusion and Immunohematology - IJBTI - Review Articles, Original Articles, Short Communication, Case Series, Case Reports, Letter to Editors
 
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Original Article
 
Analysis of the evolution of the residual risk of HIV transmission at the National Blood Transfusion Center (CNTS) of Lomé (Togo) from January 2008 to December 2012
Liza Koboyo Nadjir1, Akuété Yvon Segbena2, Jean-Pierre Cazenave3
1CNTS of Lomé, Lomé, Togo.
2Department of Laboratories, Campus Teaching Hospital of Lomé, Lomé, Togo.
3EFS-Alsace, Strasbourg, France.

Article ID: 100020IJBTINK2015
doi:10.5348/ijbti-2015-20-ED-6


Address correspondence to:
NADJIR Liza Koboyo
Lomé, Togo, BP: 4090
Phone: 00 228 92 23 37 77

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How to cite this article
Nadjir LK, Segbena AY, Cazenave JP. Analysis of the evolution of the residual risk of HIV transmission at the National Blood Transfusion Center (CNTS) of Lomé (Togo) from January 2008 to December 2012 Int J Blood Transfus Immunohematol 2015;5:29–34.


Abstract
Aims: This study aimed to:
- Analyze the HIV residual risk of transfusion at the CNTS of Lomé from January 2008 to December 2012
- Indicate future directions to strengthen blood safety.
Methods: The residual risk of HIV transmission by blood transfusion has been estimated by the indirect method proposed by SCHREIBER. This method estimates the risk that a donation was made during the immunologically silent period. Using the incident cases, we calculated the incidence rates of HIV that multiplied by the duration of the serological window period gave the residual risk of transmission.
Results: Blood donors included in study were a total of 16, 042 over the five years. Males accounted for 79. 37% and 64. 41% of donors were under 30 years. The number of cases of confirmed HIV was zero in 2008, five in 2009, five in 2010, three in 2011, two in 2012. The residual risk (RR) was respectively 1/17391 in 2009, 1/19342 in 2010, 1/43478 in 2011 and 1/181818 in 2012. From 2009 to 2012, the RR decreased by 10.45 times.
Conclusion: The residual risk was relatively high in 2009 but has gradually declined over ten times in 2012. A policy of blood donators and the orientation of the CNTS towards new technologies such as the inactivation of the pathogens might contribute to reduce appreciably the RR of diseases transmitted by the blood.

Keywords: Blood donors, residual risk, HIV, CNTS-Lomé


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Author Contributions:
Liza Koboyo Nadjir – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Akuété Yvon Segbena – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Jean-Pierre Cazenave – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2015 Liza Koboyo Nadjir et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



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